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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15f60f3538d141400de5c56d51f7cdc75652252b92b111bd70c8ea6f74c2cb8a' 
  AND token = 'xX895FMPBE57Uw4CxDE+tncCIij807SJYLTP/9z1FcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}