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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c9103b4cd50c94f97f68f8d7bd52a4daf77e9832c72a826e582b784d5291190' 
  AND token = 'S/w0pNyvA/67pzhwI92ELUTKnoZwWlf92DKV3W8Fsd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}