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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd77f0b6fe19008d30628e7b6965c1b3a5cfa9bdd963d8f704b945aee1f54a4de' 
  AND token = 'ghwlREHMusLBQ50aPqi+3dRn4GGI/RVYWrn00IR4TTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}