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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d04a1f88f20ccf252932cb06ac80d1664a31b1316e53379d0d83cabd8023a3f' 
  AND token = 'TS14t4Wp8+Yp2zJ1uqwuJl2BBD5RONKvDtE68J2XnbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}