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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46a44299e227146b6463149fab9cb62d4bcf4152e70421e02e9e358e049e7a43' 
  AND token = 'geUXEkzEF+bDHWhm1g6MtfFqrMIuvD6Fqv0WbfS7hyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}