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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '863d020997f1d767097a6fa1b72058c17b5b782dd8f88c67acfb1c35226d622b' 
  AND token = 'ER8rrH3u/CtPYOaLncZGJUTcM7c9zphE3DEv54B6Z1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}