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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57de9e16f89c70f94170b7a260a1f8a9382758149ee8b57d6598097503edc5b0' 
  AND token = 'G71kQ+h2F1fl7IN6mTA4hzf00SdOjTVjbh81x6VhmKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}