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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a73dea432dcd9365f84db71f7edbc17a4e0c390cbbceb970e928defe99ab6f9a' 
  AND token = 'eQ7vlYmg1I3TWyGailZ/GNrsZ1FC9ocvARRdt+Stv/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}