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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ca3733b6376a21e8f1903b01a98792a86a6424a05dc7caa6392d929f0d648f4' 
  AND token = 'eZZC1r9HhOe/RR9M5naFTWSmMZwNhAdgxHAa3TCvCxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}