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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce4d716801a240f136aeb685e7d186b5b97971bcaf94e1f9cc658589fcbaba97' 
  AND token = 'jyFy5JRwt355RVkOcIShr0zge0w3vFLZ2fx1cMvTgzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}