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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ea57c7ee396790031f90b4328bed3a6330bd1dbcf5e32914f3bdb0e3af2b526' 
  AND token = 'vl7QG9WE6hr2d0SAx94eTA/SVBHLSE5sKQWzNLd5qWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}