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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78d36be483617c42c17992cd96c1b3188dfd7dfefcd31d8cc024a7114c1382a6' 
  AND token = 'ERzwvIeG/wyk7T2JDMRIMXpZHfgKLs788CJCltNH6VM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}