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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e5d3d8acd56766ec849699acccbbcf5f6faa2f4e28b9a8e3a0c618fd2c632a' 
  AND token = 'gkQ0qmKdnlLDy2Y8XrVobv+N9SBuRh/Yvu4x9GdxDX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}