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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '886f68649fcde678aa36ecd2227adc257502509428fca3ab369009aa01c19cf3' 
  AND token = 'wy8ny8xlJhgmALiMm746MuXRbZ1QrRXUo+jpBh3bnlA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}