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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccc159e9e9f19d4c7902ddf09bb5a5848d52e9431ca401f2fc13357b52d846f2' 
  AND token = 'HJJ3SeVakKhsO9z1yrVWvOjSCeBPYZN1MuR3J6wdyPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}