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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cd10be80b9f1669ce09a30978134abd37fdb1ac90c5c65f789e06ece46121e5' 
  AND token = 'ID5HYudLt6/xaobCZdPO7VzIjOcYuM72itrnmyG3CyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}