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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '193d28501391d335d8801259ffa904f96286b0e6e661b9e9b32cd5c11b7177e8' 
  AND token = '33PXR5FdJiyuhBgG7Ix0M1qDO4xCWQbo3P5SxMrr1Q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}