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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44cd5330aa33a5db25ab34a69fc5762401a0d08844f1f3cec5166b12a0d99583' 
  AND token = 'w3d2MgN604vTS+BCvT2Ev8hPNNgMNSnfZrvcipaVGrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}