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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '500f1a29f79f8a0f5cf0d52b67128945afceadcfd9c1a49f5d199ae108dd95b0' 
  AND token = 'k2alDfwE8cWaApfFDN+TB1oaxxwYgj3Hf24XAFxbxvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}