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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d2444b6c46364caa1ec80236697cc0bdf56e560eec0e8a3f1a7bdf3df043f99' 
  AND token = '2xT48INkBWQRM6QKfjQUf4m9FbGX5jA9V80FrTO9DXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}