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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1460224620a1735b7b6c40b0eb1f65901b8a44eef51aa04d567614dd7a04751c' 
  AND token = 'tE0uQde8ZLpwDSR5h+clsqKXnYdJUUcNRirujHX0m+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}