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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '747c6a2d0c1d90a3eda9ec73f28663d30adbb2babc52ca63265ef678d93e835b' 
  AND token = 'daTycTqkaiIDj85FZhAUon5R4CSOMQnU6j9e9PcC0x4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}