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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd305b1a37ac7e6e75d867d77e8f5804257a0c4390a2a2eb533c6573081dccd45' 
  AND token = '5/1vevzk36qj7SKo9MiuZiUvpcgRTAbyrL033gCyFNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}