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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4565b619a7f803f991781748b91f1c05d49c95ec37a43c95ef99a89663524a2' 
  AND token = '7AaTkSrTRSPWt/qA9B/LN8X0GAvyJiUa5Zsqz1RgNCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}