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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06aae842e756722163a8321ad786d01e95f228cff9242ad79110649e3fb99245' 
  AND token = '+UVM52Bx/I0LUIVSH/3iJrL5D08CYhXfAuCdP6Hndg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}