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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6526627c2e4f37132a44441f81e6412574e1499013aa333127075320b7e6c9e7' 
  AND token = 'NSkZdqyHw25C7AJPrAsS3Vc1jZIXvZPySqc8usVVcuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}