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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64bad3e7f582b79076d43343669c25e7b2fff91d782f12090e8eaf547dd8bad4' 
  AND token = 'mlCE6lZL9FhdjDlmRCECo6SkHRb/CcrhPcLsmal/ROs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}