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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '290af06e2d2351be453386c5e5a038c1a1d5f5fd4d63aabfbe64354bfaa803eb' 
  AND token = 'MurRfrqn4CLUSzt+YH4a0fEum7a3r/gut6r9fJANf4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}