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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a2146256c47d8a8e5296dc8e7f9c8dd977ef9145353c07434eb8ac52b588a0b' 
  AND token = 'syDhewNwb9Hp9+wUy78HttgFHgiYAje6NocF12F/FsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}