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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af1674d10f22ee597b00ff9111399affb40859e99931f577b489347b0a451d3b' 
  AND token = 'lQTNNZldsZ6LM32FIt/D4mggdAZf9lww4UzpTOS4qTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}