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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ef68e77c1401d9e7640d42532d4ce297f4e0604ce5a85b838804f164b0aa471' 
  AND token = 'XmtmPmlvP31R4nFkqcQ2gUoqFyBvimS0736TiVwnot0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}