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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05ed83a911aa2072e8f2663e8de8603703b76776b75f6aa7c38068761334af50' 
  AND token = '2Xn+intxUwX5nlxxF60ftUAv9ox4q/ZPxjYZVp85nv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}