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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '461fc478e552290dd7d1bea38db3e786277d9c4e97ebbf36387c715db180a1c6' 
  AND token = 'fhhop6RCvpW0KbJ2G8NRyuWmHSIlRlhbwIxyZuMDfq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}