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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6178a10be5a9309a64dd9744842d315d9ba0fdaec51bd1b753c80dcd8715e489' 
  AND token = 'XRuwaoF+7xvOYHUK0/VHaHahOsUVUiYOjkmHh/OTozU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}