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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45854bbe72d2e2fcd59442c52ef8b846d1677418cfb48db1f77e9741e6ee1065' 
  AND token = 'G4/SPvy7mDdW6aTtG3+w7+RlQXq4pdh+E9lc/tbjsx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}