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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eeb02c441d67e467908e20dd296af0bb49ce39060c753f3c63cfd00fffadb521' 
  AND token = '37MQUlU3K2keKKvXU1O/wLJsLRzzHDhP4bR5GlnAFjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}