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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fbf4da6eefebb5ca6441305e50bb332703b555e451182c2ab9b5dedb2b5d6fb' 
  AND token = 'LF5J47CdmCdOgxprZoQet2YMYGcc6qCrTJrI7s/2GAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}