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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6441ce92de6c94de40b5bfc474d3934659816902a13f3ac973ddcdc3b192d403' 
  AND token = 'YiC9q81TTmC42hsSU30rplGYJq83PAv5kIhTjDi44+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}