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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6b278a318947e20e32cc437a6cda8515cc6817d7c597e67934af70e2147c97e' 
  AND token = '5HyCQAfyDgTg/WPj8NSChuqkI/LLzdyHp+sjmNXvqfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}