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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd010672731f5b2a4a731714d68cb6f9f394a635c357cb034e00e32d7f98e38d' 
  AND token = '+nzPPV7cOPblL3kfU0q8NlhtPSAmwwjWN8kqaz9BTHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}