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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e430dc12c9d6cd8a70736420c66f3f63e6af4dbe33ab5e7e7714d3005e1558f' 
  AND token = 'o9DyJqA0qHpr8ukv5EA+Ky0FRjqOZaTk1+9XVeaUNnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}