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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40ba5dc241f2700f9d918be91e943eac1cf12e6e04603c13dd1d0c7074ef96b8' 
  AND token = 'E6lJkn4molFHrvhVR6sHyv0v/x7H2WQJoYQnqcQ4oyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}