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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b22a53d3a94c3781a5557e0678ebad8b70bc782e42b196cbdd585cc75d3e48a' 
  AND token = 'DiRyll76i78sxMZ7OxGbf7P2bZAFLZNHyEl3tSbXD/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}