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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5df589536f368d86305bbffe4a0b9d54423c8d8632f932a7bfdbea66e77b7d4' 
  AND token = 'tVTxHaoNv+vxF9rgYqeTwrd0/Nl5V6i6Ikjw+zptW1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}