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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44417e0a83ca0fba3638a1ec53b7153927f6fdfffbe3d64f2ffcc1893d344d01' 
  AND token = 'CKYF5PpKlakUu2E6hOwafcrgiQQZIYYWTjPzoMTO6BM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}