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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f21c338101c114e45d4f66a0cee8e687c8cb2d9e43ea8cbc0dfbbe9bd3a3c48' 
  AND token = 'IM9UAtFH/nQ/2rM4K5HCddnseyqWJrAHquljKOswg60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}