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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2babcb02f2dcabd1c7201617cd13485f1ccdb213b34d603dcd14841a697d53f' 
  AND token = 'Gmen/9ymOJwQ94cD6XaoIfj6j+ZMFG1IWrZn8Z+IfAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}