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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9ac53045d67619068586925e015953915c11ecf855210bab12d735dca968593' 
  AND token = 'b9WBI5B5Pv+8Rp2kAoFspIKFfh4P6xcIoofhGMO1wOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}