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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e3e67829e0fe6e373a075127b2db40cb1ccc7862a30657fdfeb4ba2a2b89f23' 
  AND token = 'uvCl7pbJ6F4wN0NTH6339GGnXiKuvUzRnXc3qgT67ek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}