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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f77d7586406b9ff7ddffde7334ecb7b9fa707fba4935d3c2d5614941fe4701f1' 
  AND token = '57UQsnrFTcnpb+UX181823htYXZvKHSOnECW8d/WGC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}